a Record control number 000344935000003

a ISSN 1476-0584

a Original cataloging agency NEU GrandLibrary

a Language code of text/sound track or separate title eng

a Classification number QW504

b Item number .M55 2014

a Personal name Bahceciler, Nerin N.

a Title A milestone in house dust-mite-allergen immunotherapy: the new sublingual tablet S-524101 (actair).

h Medium Electronic Document

c Statement of responsibility, etc Nerin N Bahceciler, Arzu Babayigit Hocaoglu & Nilufer Galip.

c Date of publication, distribution, etc 2014.

b Name of publisher, distributor, etc Expert Reviews,

a Place of publication, distribution, etc London :

a Summary, etc Subcutaneous allergen-specific immunotherapy has long been used in the treatment of allergic rhinitis and/or asthma and its efficacy has been confirmed. However, due to the discomfort of injections and the risk of severe adverse reactions, alternative routes of allergen administration have emerged. Delivery of allergens through the mucosal route had been proposed and investigated thoroughly, confirming the sublingual route to be the most efficacious. Later, the efficacy and safety of this route have been documented by numerous controlled trials both for house dust mite (HDM) and pollens. Recently, sublingual orodispersable grass pollen allergen tablets were in use followed by the newly developed HDM allergen tablets with satisfactory clinical results: Moreover, very recently 1 year of HDM tablet treatment was demonstrated to exert its clinical efficacy 1 year after discontinuation of tablet IT. The persistence of efficacy after only 1 year of treatment is a new and promising era. Currently, Sublingual Immunotherapy is the most easily administered and safe treatment option until more immunogenic, less allergenic and more efficient allergen extracts are developed.

a Topical term or geographic name as entry element Near East University Article

a Topical term or geographic name as entry element Yakın Doğu Üniversitesi Makale

a Topical term or geographic name as entry element Immunology

a Topical term or geographic name as entry element Allergic rhinitis

a Topical term or geographic name as entry element Asthma

a Topical term or geographic name as entry element House dust mite

a Topical term or geographic name as entry element Sublingual

g Relationship information DEC 2014, Vol.13, Issue 12, p1427-1438

a Main entry heading Expert Review Of Vaccines

x International Standard Serial Number 14760584

u Uniform Resource Identifier http://library.neu.edu.tr:2048/login?url=http://dx.doi.org/10.1586/14760584.2014.972949